Sohal Laboratory

This is a list of papers by year.  For a list of papers organized roughly by subject area click here.

2024

Jackson et al., Amygdala-hippocampus somatostatin interneuron beta-synchrony underlies a cross-species biomarker of emotional state, Neuron, Jan 23 (online).

2023

Sohal, Neurobiology of schizophrenia, Current Opinion in Neurobiology, Dec 12.

Cho et al., Long-range inhibition synchronizes and updates prefrontal task activity, Nature, April 26.

2022

Malik et al., Top-down control of hippocampal signal-to-noise by prefrontal long-range inhibition, Cell, April 28.

Sohal, Transforming Discoveries About Cortical Microcircuits and Gamma Oscillations Into New Treatments for Cognitive Deficits in Schizophrenia, American Journal of Psychiatry, April.

2021

Wilke et al., Convergence of clinically relevant manipulations on dopamine-regulated prefrontal activity underlying stress-coping responses, Biological Psychiatry, Nov 12.

Frost et al., Dynamic patterns of correlated activity in the prefrontal cortex encode information about social behavior. PLoS Biology, May 3.

2020

Cunniff et al., Altered hippocampal-prefrontal communication during anxiety-related avoidance in mice deficient for the autism-associated gene Pogz. eLife, 2020 Nov 6;9:e54835.

Cho et al., Cross-hemispheric gamma synchrony between parvalbumin interneurons supports behavioral adaptation during rule shift learning. Nature Neuroscience, 2020 Jul;23(7):892-902.

Fazel Darbandi et al., Enhancing WNT Signaling Restores Cortical Neuronal Spine Maturation and Synaptogenesis in Tbr1 Mutants. Cell Rep. 2020 Apr 14;31(2):107495

Southwell et al., Interneuron Transplantation Rescues Social Behavior Deficits without Restoring Wild-Type Physiology in a Mouse Model of Autism with Excessive Synaptic Inhibition. J Neurosci. 2020 Mar 11;40(11):2215-2227.

Rubin et al., Regulatory Elements Inserted into AAVs Confer Preferential Activity in Cortical Interneurons, eNeuro Dec 17;7(6).

2019

Malik et al., Tsc1 represses parvalbumin expression and fast-spiking properties in somatostatin lineage cortical interneurons. Nat Commun. 2019 Nov 1;10(1):4994.

Sohal and Rubenstein, Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders. Mol Psychiatry. 2019 Sep;24(9):1248-1257.

Lee et al., VIP Interneurons Contribute to Avoidance Behavior by Regulating Information Flow across Hippocampal-Prefrontal Networks. Neuron. 2019 Jun 19;102(6):1223-1234.

Meda et al., Microcircuit Mechanisms through which Mediodorsal Thalamic Input to Anterior Cingulate Cortex Exacerbates Pain-Related Aversion. Neuron. 2019 Jun 5;102(5):944-959.

2018

Kirkby et al., An Amygdala-Hippocampus Subnetwork that Encodes Variation in Human Mood. Cell. 2018 Nov 29;175(6):1688-1700.

See et al., Coordinated neuronal ensembles in primary auditory cortical columns. Elife. 2018 Jun 5;7.

Marton et al., Roles of Prefrontal Cortex and Mediodorsal Thalamus in Task Engagement and Behavioral Flexibility. J Neurosci. 2018 Mar 7;38(10):2569-2578.

Martin et al., DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling. Mol Psychiatry. 2018 Feb;23(2):467-475.

2017

Athilingam et al., Serotonin enhances excitability and gamma frequency temporal integration in mouse prefrontal fast-spiking interneurons. Elife. 2017 Dec 5;6.

Robinson and Sohal, Dopamine D2 Receptors Modulate Pyramidal Neurons in Mouse Medial Prefrontal Cortex through a Stimulatory G-Protein Pathway. J Neurosci. 2017 Oct 18;37(42):10063-10073.

Wu et al., The Cytokine CXCL12 Promotes Basket Interneuron Inhibitory Synapses in the Medial Prefrontal Cortex. Cereb Cortex. 2017 Sep 1;27(9):4303-4313.

Ellwood, Patel and Wadia et al. Tonic or Phasic Stimulation of Dopaminergic Projections to Prefrontal Cortex Causes Mice to Maintain or Deviate from Previously Learned Behavioral Strategies. J Neurosci. 2017 Aug 30;37(35):8315-8329.

Khoshkhoo et al. Dynamic, Cell-Type-Specific Roles for GABAergic Interneurons in a Mouse Model of Optogenetically Inducible Seizures. Neuron. 2017 Jan 18;93(2):291-298.

2016

Kjaerby et al., Serotonin 1B Receptors Regulate Prefrontal Function by Gating Callosal and Hippocampal Inputs. Cell Rep. 2016 Dec 13;17(11):2882-2890.

Sohal, How Close Are We to Understanding What (if Anything) γ Oscillations Do in Cortical Circuits?. J Neurosci. 2016 Oct 12;36(41):10489-10495.

Luongo et al., Correlations between prefrontal neurons form a small-world network that optimizes the generation of multineuron sequences of activity. J Neurophysiol. 2016 May 1;115(5):2359-75.

Luongo et al., Putative Microcircuit-Level Substrates for Attention Are Disrupted in Mouse Models of Autism. Biol Psychiatry. 2016 Apr 15;79(8):667-75.

Marton and Sohal, Of Mice, Men, and Microbial Opsins: How Optogenetics Can Help Hone Mouse Models of Mental Illness. Biol Psychiatry. 2016 Jan 1;79(1):47-52.

2015

Vogt et al., The parvalbumin/somatostatin ratio is increased in Pten mutant mice and by human PTEN ASD alleles. Cell Rep. 2015 May 12;11(6):944-956.

Cho et al., Gamma rhythms link prefrontal interneuron dysfunction with cognitive inflexibility in Dlx5/6(+/-) mice. Neuron. 2015 Mar 18;85(6):1332-43.

2014

Cho and Sohal, Optogenetic approaches for investigating neural pathways implicated in schizophrenia and related disorders. Hum Mol Genet. 2014 Sep 15;23(R1):R64-8.

Lee et al., A class of GABAergic neurons in the prefrontal cortex sends long-range projections to the nucleus accumbens and elicits acute avoidance behavior. J Neurosci. 2014 Aug 27;34(35):11519-25.

Lee, Gee et al., Pyramidal neurons in prefrontal cortex receive subtype-specific forms of excitation and inhibition. Neuron. 2014 Jan 8;81(1):61-8.

2012

Seybold et al., Chronic reduction in inhibition reduces receptive field size in mouse auditory cortex. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13829-34.

Sohal, Insights into cortical oscillations arising from optogenetic studies. Biol Psychiatry. 2012 Jun 15;71(12):1039-45.

Gee et al., Synaptic activity unmasks dopamine D2 receptor modulation of a specific class of layer V pyramidal neurons in prefrontal cortex. J Neurosci. 2012 Apr 4;32(14):4959-71.